Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC STF-31 | 724741-75-7 | 99.8% | 423.53 | 50 MG
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STF-31 | 724741-75-7 | 99.8% | 423.53 | 50 MG
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Selleck Chemical LLC Levofloxacin 25mg 100986-85-4 Fluoroquinolone
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Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC TDZD-8 S2926-25mg
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TDZD-8 (NP 01139) is a non-ATP competitive GSK-3 inhibitor with IC50 of 2 M minimal inhibitory effect observed on CDK1 casein kinase II PKA and PKC
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Medchemexpress LLC NCT-503 | 1916571-90-8 | 99.7% | 408.48 g/mol | C20H23F3N4S | 200 MG
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NCT-503 is a small-molecule inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 2.5 μM, used as a research tool to probe serine biosynthesis pathways and PHGDH-dependent cancer biology in vitro and in vivo.
- Potent PHGDH inhibition with IC50 2.5 μM.
- High selectivity against other dehydrogenases and minimal GPCR cross-reactivity.
- Demonstrated activity in PHGDH-dependent cell lines and tumor xenograft models.
- Solid form with high purity suitable for biochemical and cellular assays.
- Recommended storage conditions for long-term stability.
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Ambeed AMBEED
5000886395 7-AMINOISOQUINOLINE 5G
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Medchemexpress LLC DYB-03 | 2982792-85-6 | 99.5% | 479.56 | 1 ML
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DYB-03 is an orally active HIF-1α/EZH2 inhibitor. It inhibits the migration, invasion, and angiogenesis of lung cancer cells and HUVECs both in vitro and in vivo. Additionally, DYB-03 induces apoptosis in A549 and H460 cells that are resistant to 2-ME2 and GSK126.
- Oral active HIF-1α/EZH2 inhibitor
- Inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs (in vitro and in vivo)
- Induces apoptosis in 2-ME2- and GSK126-resistant A549 and H460 cells
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Medchemexpress LLC STF-31 | 724741-75-7 | 99.8% | 423.53 | 5 MG
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STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC50 of 1 μM. It is also a NAMPT inhibitor and inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells.
- Selective inhibitor of glucose transporter 1 (GLUT1).
- NAMPT inhibitor.
- Inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells.
- Specifically toxic to RCC4 cells at concentrations of 0.01-10 μM, while RCC4/VHL cells are relatively unaffected.
- Causes necrotic cell death and does not induce autophagy, apoptosis, or DNA damage at concentrations of 1.25-5 μM for 3 days.
- Reduces light-induced CX3CR1gfp/+ mice microglial activation and retinal degeneration in vivo at 10 mg/kg.
- Promotes accumulation of necrotic thymocytes after Dexamethasone-induced apoptosis in vivo at 10 mg/kg.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000668843 4 7-DIHYDROXYCOUMARI 250MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000734330 2 5 -DIMETHOXY-1 1 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000668931 TRISDECANOIN 200MG
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Medchemexpress LLC (-)-Huperzine A | 102518-79-6 | 99.7% | 242.32 | 200 MG
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(-)-Huperzine A | 102518-79-6 | 99.7% | 242.32 | 200 MG
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eMolecules 90800-42-3 | 8-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | MFCD18417146 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc(O)c2ncccc2c1 | 0.25g | 528983323
8-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | 90800-42-3 | MFCD18417146 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc(O)c2ncccc2c1 | 0.25g | 528983323
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000665068 FIRMONERTINIB MESYL 10MM/1ML
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Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.18 | 5 G
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2-Aminoquinoline (2-Quinolinamine) is a promising compound identified as a bioavailable nNOS inhibitor. While it exhibits low human nNOS inhibition and limited selectivity against human eNOS, it demonstrates antiviral activity against the vaccinia virus and shows potential for research in antineurodegenerative agents.
- Acts as a nNOS inhibitor
- Exhibits antiviral activity against vaccinia virus
- Potential for antineurodegenerative agent research
- Solid appearance
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Medchemexpress LLC 1,7-Heptanediamine | 646-19-5 | 98.54% | 130.23 | 10 G
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1,7-Heptanediamine (C7) is a deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM. It appears as a solid below 26°C and a liquid above 29°C, with a colorless to off-white appearance. It is soluble in water at ≥ 100 mg/mL (767.87 mM).
- Deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM
- Appears as a solid below 26°C and a liquid above 29°C
- Colorless to off-white appearance
- Soluble in water at ≥ 100 mg/mL
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